Long non-coding RNA MALAT1 facilitates the tumorigenesis, invasion and glycolysis of multiple myeloma via miR-1271-5p/SOX13 axis
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چکیده
منابع مشابه
Evaluating the clinical importance of long-non coding RNA MALAT1 expression in breast cancer
Background: Breast cancer is one of the major causes of illness and mortality among women. Long non-coding RNAs (LncRNAs) have important role in tumor development and progression. Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a lncRNA that deregulates in several cancers, however, its value in the diagnosis of breast cancer is unclear. This study was conducted to investigate...
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Emerging evidence implicates that a large fraction of human genome was transcribed but the transcripts known as long non coding RNA are not translated into proteins. They are contributing in different cellular processes, including cellular proliferation and apoptosis. LncRNAs were found to play critical roles in many diseases and act as key regulators in malignancies. In this study, we investig...
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Dysregulation of long non-codng RNA (lncRNA) expression has been found to contribute to tumorigenesis. However, the roles of lncRNAs in BRCA1-related breast cancer remain largely unknown. In this study, we delineate the role of the novel BRCA1/lncRNA NEAT1 signaling axis in breast tumorigenesis. BRCA1 inhibits NEAT1 expression potentially through binding to its genomic binding site upstream of ...
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ژورنال
عنوان ژورنال: Journal of Cancer Research and Clinical Oncology
سال: 2020
ISSN: 0171-5216,1432-1335
DOI: 10.1007/s00432-020-03127-8